Table of Contents
Can you be allergic to marijuana

Yes. Marijuana allergies are real and clinically recognized.
Causes
- Immune Reaction: Body treats cannabis proteins as harmful, triggering IgE-mediated response.
- Allergenic Proteins:
- Can s 3 (lipid transfer protein)
- Proteins with cross-reactivity to plant foods (e.g., tomato, peach, banana)
Exposure Routes

- Inhalation: Smoke or pollen
- Contact: Touching plant material
- Ingestion: Edibles, tinctures, oils
Common Symptoms
| System | Symptoms |
|---|---|
| Respiratory | Sneezing, nasal congestion, wheezing, asthma |
| Skin | Rash, hives, itching, contact dermatitis |
| Eyes | Redness, tearing, itching |
| Gastrointestinal (rare) | Nausea, vomiting |
| Severe (rare) | Anaphylaxis (life-threatening reaction) |
Cross-Reactivity
- Allergies may also occur to:
- Tomatoes
- Bananas
- Peaches
- Latex
- Tobacco
(due to similar proteins)
Diagnosis
- Skin Prick Test: Cannabis extract applied to skin
- Blood Test: Measures cannabis-specific IgE antibodies
- Clinical History: Documented reaction after cannabis exposure
Treatment

- Avoidance: Eliminate exposure to cannabis products
- Medications: Antihistamines (mild), epinephrine (severe)
- Desensitization: Still experimental
Key Takeaway
Marijuana allergies are rare but real. They can mimic seasonal allergies or food sensitivities. Proper diagnosis and avoidance are essential for managing symptoms safely.